Pharmacology essentials
Q1. To prevent drug toxicity after overdose what is used?
A. Syrup of ipecac C.
silica
B. Activated charcoal D.
both a and b
Q.2 Drug A is more lipid soluble and acidic than drug B which of the
following is TRUE for their absorption into the glomerular filtrate?
A. Greater absorption of drug A
than drug B C.
both are absorbed equally
B. lesser absorption of drug A
than drug B D.
none of these
Q3. The action of antagonist is
A. Opposite to that of agonist C.
No action
B. Similar to action of agonist D.
same as inverse agonist
Q4. Functional antagonist is
A. Act on same receptor C.
both a and b
B. Act on different receptors D.
there is nothing called functional
Antagonist
Q5.Binding site for G protein coupled receptors is
A. outer side of membrane C.
In between alpha helix
B. inner side of membrane D.
both a and c
Q6. Sildenafil (Viagra)
A. phosphodiesterase inhibitor C.
cause vasoconstriction
B. prolongs action of c GMP D.
both a and b
Q7.Nicotinic, GABA receptors are example of
A. Enzyme linked receptors C.
Intracellular receptors
B. G protein receptors D.
ligand gated receptors
Q8.Match the following
1. Chloramphenicol a. Blue baby syndrome
2. Nimesulide b. liver toxicity
3. Aspirin c. grey baby syndrome
d. Reye’s syndrome
A. 1-a,2-b,3-c C.
1-c,2-d,3-a
B.1-c.2b,3-d D.
1-a, 2-b,3-c
Q.9 Olfactory receptors, chemokine receptors, inflammation mediators, Opsin
protein are
A. enzyme linked receptors C.
Intracellular receptors
B. G protein receptors D.
ligand gated receptors
Q. 10. Tetracycline is not taken with
A. sugar water C.
alluminium hydroxide antacid
B. milk D.
both b and c
Q11. Intraosseous route of administration is
A. bone C.plasma
B. CSF D.none
of these
Q12. Epinephrine is given with lidocaine(anesthetic) because-
A. acts as vasoconstrictor acting
leading to local effect C. for
better stability
B. for general effect D.for
slow drug release
Q13. Hyluronidase
A. increases the absorption rate
of parenteral fluids given subcutaneously
B. is used in antiaging creams
C. ophthalmic surgery, in
combination with local anesthetics
D. both a and c
Q14. People with liver diseases will show
A. Quick
drug action and low distribution of drug
B. Slow
drug action and high distribution of drug
C. Quick
action and high distribution of drug
D. Slow
drug and low distribution of drug
Q15. Administration of drug along with food
leads to
A. Slow
action of drug
B. Quick
action of drugs
C. Slow
or quick action depending on drug interaction
D. Makes
no difference
Q16. Which of the following route doesnot involve use of needle
A. Intravenous
B. Intrathecal
C. Sialistic
implants
D. Dermojets
Q17. Nicotine patches is taken transdermally
A. For
smoking cession
B. Looks
cool
C. For
people who don’t like to smoke
D. None
of these
Q18. Aspirin and naproxen are
absorbed from the stomatch because
A. Because
they are weakly basic drugs and they
dissociate to greater extent
B. Because
they are weakly acidic drugs and they dissociate to greater extent
C. Because
they are weakly acidic drugs and they don’t
dissociate to greater extent
D. Both
a and b
Q19. To overcome phenobarbital(weak acid) overdose the urine should be made
A.
Strongly Acidic
B.
Strongly
Basic
C.
Weakly basic
D.
Weakly acidic
Q20. Drug at high
concerteration shows
A.
First order kinetics
B.
Second order kinetics
C.
Zero order kinetics
D.
Third order kinetics
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